How can you access Running instance of IE and refersh page

First you need to refer SHDocVw.dll and MSHTML.dll. In Visual Studio, go to Project, Add Reference, and then select the COM tab. select these dlls.

Csharp Code:

string myUrl = www.google.com;
SHDocVw.WebBrowser m_browser = null;
SHDocVw.ShellWindows shellWindows = new SHDocVw.ShellWindowsClass();
string filename;
foreach (SHDocVw.WebBrowser ie in shellWindows)
{
filename = Path.GetFileNameWithoutExtension(ie.FullName).ToLower();
if (filename.Equals("iexplore"))
{
m_browser = ie;
//Assign Browser Document
mshtml.IHTMLDocument2 myDoc = (mshtml.IHTMLDocument2)m_browser.Document;
//URL Location
string myLocalLink = myDoc.url;
if (myLocalLink == myUrl)
m_browser.Refresh();
//break;
}

You also can do other actions using m_browser, m_browser.Document to control content ofthis page.